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1.
J Hum Nutr Diet ; 36(6): 2157-2169, 2023 12.
Artigo em Inglês | MEDLINE | ID: mdl-37767760

RESUMO

BACKGROUND: Agricultural activities in 2020 have resulted in 5.5 billion tons of CO2 equivalent globally, which is expected to rise because the food system would have to grow 70% more food for the population in 2050. Research suggests that agricultural productivity in South Asian countries, will increase food security; however, the role of their food crops and livestock products in environmental imprints is uncertain. This review aimed to assess the environmental impacts resulting from pre- and post-production agricultural activities related to edible food crops and livestock products consumed in eight South Asian countries. METHODS: Studies were retrieved using three databases (PubMed, Google Scholar and Science Direct) from 2011 to 2022. The protocol for this scoping review was not registered. RESULTS: Twenty-seven studies met the inclusion criteria. Most studies were conducted in India. Twenty-four articles assessed greenhouse gases (GHG) emissions, followed by water footprints (n = 5), nitrogen and phosphorus (N&P) emissions (n = 4), and land requirements (n = 4). The production of rice and wheat was identified as a significant contributor to GHG emissions. In India, Bangladesh and Sri Lanka, the production of livestock (meat/bovine/shrimp and milk) was reported to be harmful to the environment. Inconclusive data were retrieved for other environment variables. CONCLUSIONS: Diversification in food production and cultivating additional coarse cereals (millets) offer opportunities for GHG reduction. Nevertheless, more comprehensive and longitudinal studies for South Asian countries are essential to make precise conclusions and validate the present review.


Assuntos
Gases de Efeito Estufa , Gado , Animais , Bovinos , Humanos , Agricultura/métodos , Gases de Efeito Estufa/análise , Meio Ambiente , Índia
2.
Front Public Health ; 11: 1023907, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37050953

RESUMO

Multiple factors affect cognitive health, such as age-related changes in the brain, injuries, mood disorders, substance abuse, and diseases. While some cannot be changed, evidence exists of many potentially possibly modifiable lifestyle factors: diet, physical activity, cognitive and social engagement, smoking and alcohol consumption which may stabilize or improve declining cognitive function. In nutrition, the focus has been mainly on its role in brain development in the early years. There is a strong emerging need to identify the role of diet and nutrition factors on age-related cognitive decline, which will open up the use of new approaches for prevention, treatment or management of age-related disorders and maintaining a good quality of life among older adults. While data on effect of high protein diets is not consistent, low-fat diets are protective against cognitive decline. Several micronutrients like B group vitamins and iron, as well as many polyphenols play a crucial role in cognitive health. Mediterranean, Nordic, DASH, and MIND diets are linked to a lower risk of cognitive decline and dementia. The relationship between the gut microbiome and brain function through the gut-brain axis has led to the emergence of data on the beneficial effects of dietary fibers and probiotics through the management of gut microbes. A "whole diet" approach as well as macro- and micro-nutrient intake levels that have protective effects against cardiovascular diseases are most likely to be effective against neurodegenerative disorders too. Young adulthood and middle age are crucial periods for determining cognitive health in old age. The importance of cardio metabolic risk factors such as obesity and hypertension, smoking and physical inactivity that develop in middle age suggest that preventive approaches are required for target populations in their 40s and 50s, much before they develop dementia. The commonality of dementia risk with cardiovascular and diabetes risk suggests that dementia could be added to present non-communicable disease management programs in primary healthcare and broader public health programs.


Assuntos
Disfunção Cognitiva , Demência , Pessoa de Meia-Idade , Humanos , Adulto Jovem , Adulto , Idoso , Acontecimentos que Mudam a Vida , Qualidade de Vida , Vitaminas , Cognição , Demência/prevenção & controle
3.
Food Nutr Bull ; 43(3): 340-350, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-35531896

RESUMO

BACKGROUND: Micronutrient deficiencies are a cause of significant public health burden and loss of gross domestic product, especially in developing countries. Multiple fortified salt can potentially address this challenge at scale and in a cost-effective manner. OBJECTIVE: This laboratory-based sensory trial evaluated the acceptability of quintuple fortified salt (Q5FS), that is, iodized salt (IS) fortified with additional 4 micronutrients: iron, folic acid, vitamin B12, and zinc. Iodized salt and double fortified salt (DFS), that is, IS fortified with iron, are used for comparison. METHODS: Forty-five respondents were recruited by open invitations to the university staff and their families. Each study participant rated 10 food items each in a set of 3 identical preparations differing only in the salt used. A 5-point hedonic scale was used to rate each dish on 6 sensory attributes: appearance, color, aroma, taste, texture, and aftertaste. Finally, the dish was rated on the attribute of overall acceptability-a subjective combined score based on all sensory attributes considered together. RESULTS: Among the 3 salt types, there was no difference in scores for the sensory attributes of appearance, aroma, taste, texture, and aftertaste, and the attribute of overall acceptability. Color in IS scored significantly higher than in Q5FS and DFS, but there was no difference between the scores of DFS and Q5FS. CONCLUSIONS: The 3 salts IS, DFS, and Q5FS are comparable to each other in all sensory properties, except for color. This study concludes that Q5FS is organoleptically acceptable under ideal conditions.


Assuntos
Iodo , Ferro , Ácido Fólico , Alimentos Fortificados , Humanos , Índia , Micronutrientes , Vitamina B 12 , Vitaminas , Zinco
4.
Indian Pediatr ; 58(9): 820-825, 2021 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-34302325

RESUMO

OBJECTIVE: To evaluate the efficacy of daily supplementation of 200 mL milk fortified with 240 IU of vitamin D2 (ergocalciferol). DESIGN: Double-blind randomized controlled trial. SETTINGS: School-based study in Delhi between October and December, 2019. PARTICIPANTS: 235 healthy children aged 10-14 years. INTERVENTION: Daily supplementation of 200 mL milk fortified with 240 IU of ergocalciferol in intervention group (n=119) and 200 mL of plain milk in control group (n =116) for 3 months. OUTCOME MEASURES: Change in serum 25 hydroxy vitamin D (25(OH)D), parathyroid hormone (PTH), bone formation and resorption markers, and urinary calcium creatinine ratio (U-Ca/CrR). RESULTS: The mean (SD) baseline serum 25(OH) D level in control and fortification groups was 11.9 (3.8) and 11.4 (3.6) ng/mL (P=0.23), respectively. The serum 25(OH)D levels did not increase post-intervention with the dose used for fortification, but were significantly higher in intervention group as compared to control group [10.8 (3.4) vs 6.7 (3.5) ng/mL; P<0.001]. A higher proportion of secondary hyperparathyroidism was observed post-intervention in control (39%) than in intervention group (13.3%); P<0.001. Serum carboxy-terminal telopeptide levels were similar in both groups but the serum procollagen type1 N-terminal propeptide levels were higher in the control than intervention group (P<0.007), following supplementation. CONCLUSIONS: Supplementation of milk fortified with approximately 240 IU vitamin D2 for three months did not achieve sufficient serum 25(OH)D levels in Indian children with vitamin D deficiency during winter.


Assuntos
Ergocalciferóis , Deficiência de Vitamina D , Animais , Criança , Colecalciferol , Suplementos Nutricionais , Método Duplo-Cego , Alimentos Fortificados , Humanos , Leite , Hormônio Paratireóideo , Instituições Acadêmicas , Vitamina D , Deficiência de Vitamina D/tratamento farmacológico , Deficiência de Vitamina D/prevenção & controle
5.
Altern Ther Health Med ; 24(2): 36-43, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28646806

RESUMO

Context • Coronary heart disease (CHD) is a major public health problem in developing and developed countries. Elevated cholesterol levels, especially low-density lipoprotein (LDL) cholesterol, and the emergence of CHD, have been positively correlated in many clinical and epidemiological studies. The health benefits of probiotics have received a great deal of attention, including their blood cholesterol-lowering effects on humans. Objective • The research team intended to determine the current state of research examining the effects of various probiotic strains on lipid profiles, including measures in serum of total cholesterol, LDL cholesterol, triglycerides, and high-density lipoprotein (HDL) cholesterol. Design • The review examined studies, in both animal and human models and focused on the potential of various probiotic strains to be dietary adjuncts in lowering levels of serum cholesterol with the aim of reducing the risk of cardiovascular disease (CVD) and CHD. Articles were reviewed systematically from Web search bases including PubMed and Cochrane Clinical Trial Registry. Articles meeting the inclusion search criteria were selected for further review and analysis. Only randomized controlled trials evaluating the effects of probiotics on lipid profiles in animals or humans were considered for inclusion in the review. Setting • The selection of articles and further inclusion in the review was performed in Institute of Home Economics, University of Delhi (New Delhi, India). Results • Some of the studies, in both animal and human models, have revealed that several strains were able to improve at least 1 lipid fraction. Although the results from animal studies have been fairly consistent, the findings from studies on humans have varied. Some strains when evaluated in human studies have shown insignificant effects on lipid fractions. Conclusions • Although several mechanisms for cholesterol removal by probiotics have been proposed, they need further investigation to be validated.


Assuntos
Hipercolesterolemia/tratamento farmacológico , Lipídeos/sangue , Probióticos , Animais , Doenças Cardiovasculares , Modelos Animais de Doenças , Humanos , Probióticos/farmacologia , Probióticos/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto , Fatores de Risco
6.
Nutr Rev ; 75(12): 990-1006, 2017 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-29202192

RESUMO

Pulses, defined as dry-harvested leguminous crops, include several varieties of beans, peas, lentils, and chickpeas. There is no consensus around a recommended serving size of pulses within a balanced diet, which prevents the development of transregional strategies that rely on consistent messaging to drive increases in consumption. The purpose of this review is to define and disseminate an appropriate target for a minimum serving size of pulses on any given day that can be used in international or collaborative strategies to promote the consumption of pulses. Relevant data were reviewed to examine dietary guidelines across jurisdictions, determine consumption levels of pulses across the globe, evaluate the nutritional composition of pulses in the context of dietary nutrient insufficiency, and assess the impact of pulses on dietary quality. Across a variety of pulses, 100 g of cooked pulses aligned with most regional serving sizes for pulses and provides significant levels of nutrients that are underconsumed by specific age-sex groups. Moreover, 100 g of pulses provides a number of nutrients that qualify for nutrient content claims under regional regulatory frameworks. The data demonstrate that 100 g or 125 mL (0.5 metric cup) of cooked pulses is a reasonable target for aligning strategies that promote the dietary and nutritional attributes of these legumes.


Assuntos
Dieta , Fabaceae , Comportamento Alimentar , Promoção da Saúde , Política Nutricional , Tamanho da Porção de Referência , Adulto , Humanos , Estado Nutricional , Valor Nutritivo , Verduras
7.
BMC Public Health ; 17(Suppl 2): 404, 2017 06 13.
Artigo em Inglês | MEDLINE | ID: mdl-28675135

RESUMO

BACKGROUND: South Asian countries experience some of the highest levels of child undernutrition in the world, strongly linked to poor infant and young child feeding (IYCF) practices. Strong and responsive policy support is essential for effective interventions to improve IYCF. This study aimed to identify opportunities for strengthening the policy environment in the region to better support appropriate infant and young child feeding. METHODS: We mapped policies relevant to infant and young child feeding in India, Pakistan, Bangladesh, Sri Lanka and Nepal, based on a common matrix. The matrix described potentially relevant policies ranging from high-level strategic policy documents to implementation-level guidelines. We analyzed the data based on themes focused on caregiver interactions with IYCF interventions: provision of correct information to mothers, training of frontline workers, enabling mothers to engage with service providers and strategic support for IYCF. RESULTS: Policy support for IYCF was present in relation to each of the themes assessed. In all countries, there was support for nutrition in National Development Plans, and all countries had some level of maternity protection and restrictions on marketing of breast milk substitutes. Sectoral and implementation-level policy documents contained provisions for system strengthening for IYCF and for training of frontline workers. CONCLUSIONS: The key opportunities for strengthening IYCF policy support were in relation to translating strategic directives into implementation level documents; improving multi-sectoral support and coordination; and increased clarity regarding roles and responsibilities of frontline workers interacting with mothers. These findings can support efforts to strengthen IYCF policy at the national and regional level.


Assuntos
Saúde da Criança , Dieta , Comportamento Alimentar , Promoção da Saúde/métodos , Saúde do Lactente , Política Nutricional , Adulto , Bangladesh , Aleitamento Materno , Transtornos da Nutrição Infantil/prevenção & controle , Fenômenos Fisiológicos da Nutrição Infantil , Pré-Escolar , Feminino , Humanos , Índia , Lactente , Masculino , Mães , Nepal , Estado Nutricional , Paquistão , Formulação de Políticas , Sri Lanka
8.
BMC Public Health ; 17(Suppl 2): 461, 2017 06 13.
Artigo em Inglês | MEDLINE | ID: mdl-28675136

RESUMO

BACKGROUND: Over the last decade, infant and young child feeding (IYCF) indicators in India have improved. However, poor IYCF practices are still apparent, associated with pervasive high rates of child under-nutrition. Interventions to improve IYCF need augmentation by appropriate policy support to consolidate gains. The aim of this study was to identify opportunities to strengthen and support IYCF policies through a policy content and stakeholder network analysis. METHODS: IYCF policies and guidelines were systematically mapped and coded using predetermined themes. Six 'net-map' group interviews were conducted for stakeholder analysis with data analyzed using ORA (organizational risk analyzer, copyright Carley, Carnegie Mellon University) software. The study was carried out at a national level and in the states of Maharashtra and unified Andhra Pradesh. RESULTS: Thirty relevant policy documents were identified. Support for IYCF was clearly apparent and was actioned within sectoral policies and strategic plans. We identified support for provision of information to mothers and caregivers in both sectoral and high-level/strategic policy documents. At a sectoral level, there was support for training health care workers and for enabling mothers to access IYCF. Opportunities to strengthen policy included expanding coverage and translating policy goals into implementation level documents. At the national level, Ministry of Women and Child Development [MoWCD], Ministry of Health and Family Welfare [MoHFW] and the Prime Minister's Nutrition Council [PMNC] were the most influential actors in providing technical support while MoHFW, MoWCD, and Bill Melinda Gates Foundation were the most influential actors in providing funding and were therefore influential stakeholders in shaping IYCF policies and programs. CONCLUSION: We identified a wide range of strengths in the IYCF policy environment in India and also opportunities for improvement. One key strength is the integration of IYCF policies into a range of agendas and guidelines related to health and child development service delivery at the national and state level. However, the lack of a specific national policy on IYCF means that there is no formal mechanism for review and monitoring implementation across sectors and jurisdictions. Another opportunity identified is the development of IYCF policy guidelines in emergencies and for tribal populations.


Assuntos
Saúde da Criança , Dieta , Comportamento Alimentar , Promoção da Saúde/métodos , Saúde do Lactente , Política Nutricional , Participação dos Interessados , Aleitamento Materno , Desenvolvimento Infantil , Fenômenos Fisiológicos da Nutrição Infantil , Pré-Escolar , Feminino , Humanos , Índia , Lactente , Masculino , Mães , Estado Nutricional , Políticas
9.
Lipids Health Dis ; 16(1): 113, 2017 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-28606084

RESUMO

BACKGROUND: Nutritional modulation remains central to the management of metabolic syndrome. Intervention with cinnamon in individuals with metabolic syndrome remains sparsely researched. METHODS: We investigated the effect of oral cinnamon consumption on body composition and metabolic parameters of Asian Indians with metabolic syndrome. In this 16-week double blind randomized control trial, 116 individuals with metabolic syndrome were randomized to two dietary intervention groups, cinnamon [6 capsules (3 g) daily] or wheat flour [6 capsules (2.5 g) daily]. Body composition, blood pressure and metabolic parameters were assessed. RESULTS: Significantly greater decrease [difference between means, (95% CI)] in fasting blood glucose (mmol/L) [0.3 (0.2, 0.5) p = 0.001], glycosylated haemoglobin (mmol/mol) [2.6 (0.4, 4.9) p = 0.023], waist circumference (cm) [4.8 (1.9, 7.7) p = 0.002] and body mass index (kg/m2 ) [1.3 (0.9, 1.5) p = 0.001] was observed in the cinnamon group compared to placebo group. Other parameters which showed significantly greater improvement were: waist-hip ratio, blood pressure, serum total cholesterol, low-density lipoprotein cholesterol, serum triglycerides, and high-density lipoprotein cholesterol. Prevalence of defined metabolic syndrome was significantly reduced in the intervention group (34.5%) vs. the placebo group (5.2%). CONCLUSION: A single supplement intervention with 3 g cinnamon for 16 weeks resulted in significant improvements in all components of metabolic syndrome in a sample of Asian Indians in north India. TRIAL REGISTRATION: The clinical trial was retrospectively registered (after the recruitment of the participants) in ClinicalTrial.gov under the identification number: NCT02455778 on 25th May 2015.


Assuntos
Composição Corporal/efeitos dos fármacos , Cinnamomum zeylanicum , Insulina/sangue , Síndrome Metabólica/dietoterapia , Administração Oral , Adulto , Povo Asiático , Glicemia/efeitos dos fármacos , Índice de Massa Corporal , Dieta , Método Duplo-Cego , Feminino , Humanos , Insulina/genética , Lipoproteínas HDL/sangue , Lipoproteínas HDL/genética , Masculino , Síndrome Metabólica/genética , Síndrome Metabólica/fisiopatologia , Metaboloma/efeitos dos fármacos , Metaboloma/genética , Pessoa de Meia-Idade , Fitoterapia , Triglicerídeos/sangue , Relação Cintura-Quadril
10.
Curr Diabetes Rev ; 13(5): 477-481, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-27550056

RESUMO

INTRODUCTION: Optimal infant and young child feeding, which includes initiation of breastfeeding within one hour of birth, exclusive breastfeeding for first six months, age appropriate complementary feeding after six months along with continued breastfeeding for 2 years and beyond, is a public health intervention to prevent child morbidity, mortality and malnutrition [1]. In India, even though institutional delivery rates are increasing, only 44% women are able to breastfeed their babies within one hour of delivery. While 65% children are exclusively breast fed for the first six months, the median duration of breastfeeding is 24.4 months and complementary feeding rates are 50%. To achieve optimal IYCF practices, each woman should have access to a community based IYCF counseling support system. Efforts are therefore needed to upgrade skill based training of health workers and revive and update the Baby Friendly Hospital Initiative (BFHI). To promote and sustain breastfeeding amongst working women, it is essential to ensure adequate maternity leave, crèches at work place, flexible working hours, and provision of physical space for breast feeding at work place. It is imperative to also create public awareness about the dangers of bottle and formula feeding and to provide accurate information on the appropriate complementary food to be given to infants. CONCLUSION: In conclusion, India needs to make serious efforts to overcome malnutrition with not only prioritized IYCF policies but also their effective implementation in place.


Assuntos
Cuidado da Criança/tendências , Comportamento Alimentar , Cuidado do Lactente/tendências , Fenômenos Fisiológicos da Nutrição do Lactente , Aleitamento Materno/estatística & dados numéricos , Aleitamento Materno/tendências , Criança , Cuidado da Criança/métodos , Comportamento Alimentar/etnologia , Humanos , Índia/epidemiologia , Lactente , Cuidado do Lactente/métodos , Fenômenos Fisiológicos da Nutrição do Lactente/etnologia , Fenômenos Fisiológicos da Nutrição do Lactente/normas , Recém-Nascido
11.
Indian J Public Health ; 60(4): 280-286, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27976649

RESUMO

Human studies on the effects of probiotics on lowering blood cholesterol levels have not yielded conclusive results. A meta-analysis of randomized controlled trials evaluating the effect of probiotics on lipid profile was conducted. Articles were reviewed systematically from web search bases; PubMed, Cochrane Clinical Trial Registry. Those studies which were meeting the inclusion criteria-providing matching placebo, at least single blind for probiotics and placebo, providing mean and standard deviations and not involving the use of probiotics were selected. 14 studies from 12 randomized controlled trials were analyzed providing information of 606 normo/hypercholesterolemic patients using Review Manager 5.3 (The Cochrane Collaboration, Oxford, UK). The pooled mean net change for total cholesterol (TC) is -8.40 mg/dl (-13.63, -3.61), for low-density lipoprotein (LDL) is -6.63 mg/dl (-10.63, -2.63), for high-density-lipoprotein-cholesterol is 0.59 mg/dl (-0.92, 2.09), and for triglycerides is -1.32 mg/dl (-6.49, 3.85). The findings of the analysis conclude that probiotics supplementation does lower serum TC and LDL-cholesterol levels significantly and hence a reduction in the risk factor of developing coronary heart disease.


Assuntos
Hipercolesterolemia , Probióticos , LDL-Colesterol , Humanos , Hipercolesterolemia/tratamento farmacológico , Índia , Probióticos/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto , Método Simples-Cego
12.
Indian J Community Med ; 41(3): 228-34, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27385878

RESUMO

INTRODUCTION: There is need for employing strategies to minimize measurement errors while administering semi-quantitative FFQ. The current study was planned to adapt and standardize locally available portion sizes for semi-quantitative FFQ to improve its validity and document the process of standardization of portion sizes. METHODOLOGY: The study was conducted in 9 villages of the INCLEN-SOMAARTH DDESS (Demographic, Development and Environmental Surveillance Site), Palwal district, Haryana, India. The subjects in these nine villages are part of a cohort study to assess the interaction between societal and household factors with food intake and physical activity of children. Systematic utensil survey was undertaken in 3 randomly chosen households per village i.e. 27 households and the portion sizes were derived from a total of 74 serving utensils. The derived sizes were classified as small (240 ml), medium (320 ml) and large (600 ml). The semi-quantitative FFQ with locally derived portion sizes was then administered to 63 children in 6-12 year age group. RESULTS: The volume of food measured by the reference portion sizes generally being employed in the national surveys, would have been underestimated the food consumed by the child by 55-60% as compared to what was being consumed by the children in the study area. The correlation between food intake assessed by 24-hr recall method and FFQ using derived (local) portion sizes was better as compared to that obtained with the semi-quantitative FFQ done with reference portions. CONCLUSION: In conclusion, local portion size adaptation of FFQ for semi-quantification is useful to mitigate measurement errors associated with this technique.

13.
Altern Ther Health Med ; 21 Suppl 3: 34-42, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26348612

RESUMO

Coronary heart disease (CHD) is the leading cause of morbidity and mortality worldwide. Modifiable risk factors of CHD have been identified, including high levels of low-density lipoproteins (LDLs) and triglycerides (TGs). Attempts by various researchers have been made to alter them. Several approaches, both pharmacological and nonpharmacological, have been identified to deal with the soaring numbers of individuals with those high levels. Current CHD treatment includes dietary interventions and use of statins, fibrates, niacin, cholesterol absorption inhibitors, and bile acid sequestrants. Those formulations have limitations and can possess long-term, unwanted side effects, and, therefore, other cholesterol-lowering, dietary adjuncts need to be identified and supplemented. Prebiotics are indigestible, fermented food substrates that selectively stimulate the growth and increase the activity of 1 or a limited number of microbial genus species, thereby changing the composition of the gut microbiota to confer health benefits to the hosts. Prebiotics are also nondigestible carbohydrates with specific fermentative properties, stimulating specific microbial growth associated with health and well-being. Some animal and human studies have provided strong evidence that suggests that prebiotics, as functional foods, can positively alter an individual's serum lipid profile, thereby lowering his or her risk of developing CHD. Therefore, the current review focuses on evaluating the role of prebiotics as potential dietary adjuncts in lowering cholesterol levels, with the aim of reducing the risks of cardiovascular and CHD.

14.
J Am Coll Nutr ; 34(1): 42-8, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25648211

RESUMO

OBJECTIVE: The present study is aimed at determining the effect of supplementing the diet of postmenopausal women with soy isoflavones on blood pressure and hormonal levels and providing relief from symptoms. METHOD: This research was conducted in Imam Khomeini Hospital, Ahvaz, Iran. In this double-blind experimental controlled study, 61 postmenopausal women were randomly assigned to either an experimental group (soy isoflvone, n = 30) or control group (placebo, n = 31). The subjects in the experimental group were given a supplementation of 33 g of soy in the form of biscuits that contained approximately 54 mg isoflavones for a period of 8 weeks. RESULTS: Soy isoflavones supplementation made a significant difference in the severity and intensity of symptoms as determined by the Kuppermann index. On supplementation with soy the intensity of symptoms among the subjects decreased significantly and the mean total score from 26.8% at pre phase decreased to 9.38% at post phase (p < 0.001). In the present study, the level of follicular stimulating hormone (FSH) and luteinizing hormone (LH) in the experimental group decreased after intervention with soy. This reduction in FSH and LH was highly significant as tested by repeated measures analysis of variance (ANOVA; p < 0.001). After intervention with soy, a slight reduction in systolic and diastolic blood pressure was recorded in the experimental group, indicating the beneficial effect of soy isoflavones on regulating blood pressure. CONCLUSION: This study suggests that soy supplementation could be recommended as an alternative therapy to hormone replacement therapy for control of postmenopausal symptoms.


Assuntos
Pressão Sanguínea/efeitos dos fármacos , Suplementos Nutricionais , Hormônio Foliculoestimulante/sangue , Isoflavonas/uso terapêutico , Hormônio Luteinizante/sangue , Pós-Menopausa/efeitos dos fármacos , Proteínas de Soja/uso terapêutico , Método Duplo-Cego , Feminino , Humanos , Irã (Geográfico) , Pessoa de Meia-Idade , Pós-Menopausa/sangue , Pós-Menopausa/fisiologia
15.
Indian J Community Med ; 39(3): 161-8, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25136157

RESUMO

BACKGROUND: Importance of nutrition in human immunodeficiency virus (HIV) is well-established; however, the information regarding the diet quality of people living with HIV (PLHIV) especially in India is lacking. OBJECTIVES: The objective of this study is to assess the anthropometric and nutritional profile of Indian PLHIV. MATERIAL AND METHODS: The study was performed on 400 adult PLHIV registered at the Antiretroviral Center (ART) center in New Delhi, India. Anthropometric data including height, weight, waist, hip, mid arm, and calf circumferences, were collected; 1-day 24-h dietary recall was done to gather nutrient intake from which nutrient adequacy ratios were computed. Mini Nutritional Assessment (MNA) was also conducted. RESULTS: The mean body mass index (BMI) of the sample was 19.73 ± 3.55 kg/m(2) with around 40% having BMI <18.5 kg/m(2) . All anthropometric measurements were found to correlate positively and significantly with CD4 count (P < 0.05). The sample consumed poor quality of diet as they could not meet even the 2/3(rd) of the Indian Council of Medical Research (2010) requirements for energy, protein, calcium, iron, riboflavin, niacin, folic acid, B12, copper, and zinc. Classification of subjects according to MNA indicated that more than 50% of the sample was at-risk of malnutrition and 34% were malnourished. With 40% of sample having BMI less than normal, 50% at risk of malnutrition together with poor nutrient intakes over a long period of time could contribute to further worsening of the nutritional status. CONCLUSION: There is a need to develop a database on nutritional profile of PLHIV in India which reinforces the need for development of effective strategies to improve their nutritional status.

16.
J Health Popul Nutr ; 31(2): 195-201, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23930337

RESUMO

This descriptive study investigated the nutrition-related knowledge, attitude, and practices (KAP) among people living with HIV/AIDS (PLHIV) in India. Data relating to nutritional KAP and sociodemographic profile were gathered from a sample of 400 PLHIV from New Delhi, India, using preset multiple-choice questionnaire. The knowledge on HIV/AIDS was low; nutritional knowledge was moderate as 80% of respondents could answer 4 out of 7 questions correctly. The attitude toward disease and food was positive but the application of nutritional knowledge was lacking as indicated by the moderate practice score of 8.1 +/- 2.3 out of a total score of 15. There were no significant differences in scores between genders. The PLHIV had knowledge about importance of nutrition during infection, had positive attitude toward the disease and the importance of nutrition during the course of the disease but translation of this knowledge into practice was low. Thus, there is a need for continuous interventions primarily aiming at behaviour change to convert knowledge into healthy dietary practices.


Assuntos
Dieta/métodos , Dieta/estatística & dados numéricos , Conhecimentos, Atitudes e Prática em Saúde , Adulto , Atitude Frente a Saúde , Dieta/psicologia , Feminino , Infecções por HIV , Humanos , Índia , Masculino , Pessoa de Meia-Idade , Distribuição por Sexo , Fatores Socioeconômicos , Inquéritos e Questionários , Adulto Jovem
17.
Indian J Community Med ; 37(3): 165-9, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23112442

RESUMO

CONTEXT: HIV/AIDS is known to affect an individual not only physically but also mentally, socially, and financially. It is a syndrome that builds a vacuum in a person affecting his/her life as a whole. AIMS: The purpose of the present study is to evaluate the quality of life (QOL) of people living with HIV/AIDS (PLHIV) receiving ART and its association with Body mass index (BMI) and CD4 count. STUDY DESIGN: An observational study was performed on PLHIV receiving ART in Orissa, India. MATERIALS AND METHODS: Data on sociodemographic profile, BMI, and CD4 were gathered from 153 HIV-positive subjects. QOL was assessed using WHOQOL-HIV BREF scale. RESULTS: The overall QOL score of the subjects was moderate; PLHIV with lower BMI also had poorer QOL (P<0.05). Employment affected only the social health domain of the subjects. Men reported poorer level of independence and physical health while women reported poorer social relationships and environment. All the six domains correlated significantly with the overall QOL indicated by the G-facet. CONCLUSION: Attention toward improving the nutritional status of PLHIV should be accorded high priority to ensure improvement in the overall QOL of PLHIV.

18.
Diabetes Technol Ther ; 14(1): 83-98, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21988275

RESUMO

India is currently undergoing rapid economic, demographic, and lifestyle transformations. A key feature of the latter transformation has been inappropriate and inadequate diets and decreases in physical activity. Data from various parts of India have shown a steady increase in the prevalence of lifestyle-related diseases such as type 2 diabetes mellitus (T2DM), the metabolic syndrome, hypertension, coronary heart disease (CHD), etc., frequently in association with overweight or obesity. Comparative data show that Asian Indians are more sedentary than white Caucasians. In this review, the Consensus Group considered the available physical activity guidelines from international and Indian studies and formulated India-specific guidelines. A total of 60 min of physical activity is recommended every day for healthy Asian Indians in view of the high predisposition to develop T2DM and CHD. This should include at least 30 min of moderate-intensity aerobic activity, 15 min of work-related activity, and 15 min of muscle-strengthening exercises. For children, moderate-intensity physical activity for 60 min daily should be in the form of sport and physical activity. This consensus statement also includes physical activity guidelines for pregnant women, the elderly, and those suffering from obesity, T2DM, CHD, etc. Proper application of guidelines is likely to have a significant impact on the prevalence and management of obesity, the metabolic syndrome, T2DM, and CHD in Asian Indians.


Assuntos
Consenso , Diabetes Mellitus Tipo 2/epidemiologia , Diabetes Mellitus Tipo 2/prevenção & controle , Atividade Motora , Obesidade/epidemiologia , Obesidade/prevenção & controle , Diabetes Mellitus Tipo 2/etnologia , Feminino , Humanos , Índia/epidemiologia , Masculino , Obesidade/etnologia , Prevalência , Comportamento de Redução do Risco
19.
Indian J Med Res ; 134: 307-13, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21985813

RESUMO

BACKGROUND & OBJECTIVES: Peak bone mass, a major determinant of osteoporosis is influenced by genetic, nutritional, lifestyle and hormonal factors. This study was designed to evaluate the impact of sports training on dietary intake and bone mineral and metabolic parameters in young healthy Indian females. METHODS: Healthy female college going students (N=186, sportswomen, 90; controls 96) in the age group of 18-21 yr, residing in New Delhi (India) were evaluated for anthropometry, biochemistry (serum total and ionic calcium, phosphorus, total alkaline phosphatase, 25-hydroxyvitamin D & parathyroid hormone), diet, physical activity and lifestyle. Bone mineral density (BMD) at hip, forearm and lumbar spine were studied using central DXA. RESULTS: Sports related physical activity (3 vs. 0 h/day, P < 0.001) and direct sunlight exposure (120 vs. 30 min/day, P < 0.001) were significantly higher in sportswomen than in controls with sedentary lifestyle. Significantly higher intake of all macronutrients (energy, protein, carbohydrates and fat) and dietary calcium was noted in the diets of sportswomen. Mean serum 25(OH)D levels were significantly higher (53.0 ± 18.9 vs. 12.9 ± 7.7 nmol/l; P < 0.001) while PTH (35.3 ± 17.6 vs. 51.7 ± 44.9 pg/ml; P < 0.001) and ALP levels (194.0 ± 51.0 vs. 222.1 ± 51.4 IU/l; P<0.001) were significantly lower in sportswomen when compared to controls. No significant difference was found in ionized calcium and inorganic phosphorus in the two groups. Significantly higher (P < 0.001) total BMD and BMD at all sites except femur neck were found in sportswomen than controls (P < 0.001). INTERPRETATION & CONCLUSIONS: Physical activity, optimal nutrition and adequate sun exposure are vital for attaining peak bone mass.


Assuntos
Densidade Óssea/fisiologia , Dieta , Exercício Físico , Estado Nutricional/fisiologia , Fosfatase Alcalina/sangue , Análise de Variância , Antropometria , Cálcio/sangue , Feminino , Humanos , Índia , Estilo de Vida , Hormônio Paratireóideo/sangue , Fósforo/sangue , Radioimunoensaio , Esportes , Luz Solar , Vitamina D/análogos & derivados , Vitamina D/sangue , Adulto Jovem
20.
Diabetes Technol Ther ; 13(6): 683-94, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21488798

RESUMO

India is undergoing rapid nutritional transition, resulting in excess consumption of calories, saturated fats, trans fatty acids, simple sugars, salt and low intake of fiber. Such dietary transition and a sedentary lifestyle have led to an increase in obesity and diet-related non-communicable diseases (type 2 diabetes mellitus [T2DM], cardiovascular disease [CVD], etc.) predominantly in urban, but also in rural areas. In comparison with the previous guidelines, these consensus dietary guidelines include reduction in the intake of carbohydrates, preferential intake of complex carbohydrates and low glycemic index foods, higher intake of fiber, lower intake of saturated fats, optimal ratio of essential fatty acids, reduction in trans fatty acids, slightly higher protein intake, lower intake of salt, and restricted intake of sugar. While these guidelines are applicable to Asian Indians in any geographical setting, they are particularly applicable to those residing in urban and in semi-urban areas. Proper application of these guidelines will help curb the rising "epidemics" of obesity, the metabolic syndrome, hypertension, T2DM, and CVD in Asian Indians.


Assuntos
Diabetes Mellitus/prevenção & controle , Dieta/etnologia , Síndrome Metabólica/prevenção & controle , Política Nutricional , Necessidades Nutricionais/etnologia , Obesidade/prevenção & controle , Adolescente , Adulto , Idoso , Conferências de Consenso como Assunto , Feminino , Promoção da Saúde/tendências , Humanos , Índia , Masculino , Pessoa de Meia-Idade , Caracteres Sexuais , Adulto Jovem
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